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Levitra Original (Vardenafil)
Levitra is a drug designed to enhance erection, restore and support the health of the male reproductive system. The active component of the drug is Vardenafil. It is successfully used in the treatment of erectile dysfunction, impotence and other symptoms of sexual impotence in men. The drug enhances erection and increases the duration of intercourse. Increases the severity of sexual sensations. Visibly improves orgasm. The tablets take effect half an hour after use and remain effective for twelve hours. They cause at least 6 erections during the action, and increase the duration of sex to 80 minutes.
When excited in the nerve endings of the penis, nitric oxide is released, which increases the level of cGMP, which creates the possibility of a significant increase in blood flow to the genitals. The condition of the vessels and arteries stabilizes, more blood enters and the male member grows in size. Vardenafil temporarily (for 10-12 hours) inhibits PDE-5, which destroys cGMP and complicates the onset of an erection.
Indication for Use
Levitra vardenafil is allowed to be taken by all sexually mature men up to 65 years of age. It is recommended to take men with a flaccid erection against the background of severe overwork, with chronic fatigue, lack of sleep and a sedentary lifestyle. Men with weak erections due to reduced immunity, after stress, men with neurosis, after depression, and during age-related changes in the body. Helps improve erection and increases the duration of sex. Increases the severity of sexual sensations. Visibly improves orgasm.
Dose and Usage
Levitra Original is produced in form of small, round, yellow 20mg tablet.
Take Levitra Original inside independently on food intake. The recommended starting dose is 10 mg. The tablet should be taken 15-25 minutes before the start of sexual intercourse, but can be taken 4-5 hours later. To achieve the desired effect with Levitra, adequate sexual stimulation is necessary. Given the effectiveness and tolerability of the drug, the dose can be increased to 20 mg or reduced to 5 mg. The maximum recommended dose of Levitra is 20 mg, the frequency of administration is no more than 1 time per day.
There is no need to adjust the dosing regimen in the elderly, patients with renal failure or minor impairment of liver function. In patients with moderately severe impaired liver function, vardenafil clearance is reduced, therefore, the initial dose of the drug should not exceed 5 mg / day. Given the effectiveness and tolerability in the future, the daily dose of Levitra can be increased to 10–20 mg.
Hypersensitivity to the components of the drug, the simultaneous use of nitrates or any NO donors (drugs emitting NO), the age of 16 years, the simultaneous use of HIV protease inhibitors indinavir and ritonavir, since they are potential inhibitors of CYP 3A4.
Usually Levitra Original is well tolerated, side effects are transient and slightly pronounced.
The most common: headache, flushing (facial flushing); frequent: dizziness, dyspeptic symptoms, nausea, nasal congestion; infrequent: photosensitivity of the skin, hypertension, back pain, lacrimation; single: arterial hypotension, myalgia, priapism.
Rare cases of anterior ischemic neuropathy of the optic nerve were noted (as a result, vision decreases until its permanent loss), which is believed to be associated with the use of PDE-5 inhibitors, to which Levitra belongs. Most of the examined patients were exposed to vascular risk (severe stagnation of the optic nerve, age 50 years or more, diabetes, hypertension, cardiovascular disease, hyperlipidemia and smoking). However, it has not been established whether these single cases of the disease directly relate to the use of PDE-5 inhibitors in patients at vascular risk, or whether they should be attributed to other factors.
If the recommended dosage is regularly exceeded, systemic back pain may occur that is difficult to treat. Since vardenafil (the active component of Levitra) is highly bound to plasma proteins, the effectiveness of hemodialysis is unlikely.